Thursday, December 12, 2019
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Philippa Taylor: Paying poor young women £500 for painful and risky egg donation raises ethical questions

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Journalists and commentators covering the ‘three-parent’ embryos news consistently fail to consider, let alone ask the scientists about, several important ethical and safety questions.

There are plenty of questions asked about whether the new research will be safe for the embryos created. I’ve covered that important aspect here.

But no questions have been asked about the safety of the women who are key to creating these ‘three-parent’ embryos? Does their health and well being count for nothing?

A few sharp eyed readers of the latest news on the creation of three-parent embryos might have noted that the researchers used 523 eggs ‘donated’ by 64 women.  From this it seems that they used 240 embryos (not that this is stated clearly in the paper, it had to be dug out and analysed).

That is a large number of eggs and embryos. How did the researchers manage to get hold of so many eggs for this, considering that egg extraction is a painful, unpleasant and risky procedure requiring high doses of powerful hormones?

An advert for donors in the Newcastle area last year gives us a big clue:

Egg donors needed to help with pioneering Newcastle medical technique

Our team at the Newcastle University is pioneering the development of new techniques to prevent transmission of diseases caused by mutations in mitochondrial DNA.

We are looking for fit, healthy women between the ages of 21-35 years old who are willing to donate their eggs. Donors will receive £500 compensation for a completed donation cycle.’

So, in order to do this research, the researchers appealed directly to young fertile women, by offering payment (sorry, ‘compensation’) without any mention of any potential health risks involved. This is how they got hold of most of the eggs.

Did the researchers get hold of eggs any other ways?

Again, deep in the paper itself, behind a paywall, the paper says this:

’Human oocytes (523) included in this study were donated either by women undergoing infertility treatment (44 oocytes from 6 donors, age range 25–36 years) as part of an ‘egg sharing’ programme, or by non-patient donors (479 oocytes from 57 donors, age range 21–36 years)… Non-patient donors received financial compensation of £500 per donation cycle.’

They go on to say that £1500 was given to women who were using IVF and who ‘shared’ their eggs. Any of those women who did not become pregnant were given one additional, fully funded, IVF treatment cycle.

Aside from the ethics of ‘buying’ eggs from women, through different inducements, what are the physical risks for women?

Well, we don’t actually know for sure. It is well known that there are some risks involved and that the procedure is not pleasant or easy (hence the need for inducements) but the Government has admitted that there is no definitive data on the number of women who have been hospitalised for ovarian hyperstimulation syndrome (OHSS) after egg donation.

However we do know that just under half of 864 reported clinical incidents between 2010-2012 were due to OHSS. And: ‘Each year approximately 60 instances of severe OHSS and 150 cases of moderate OHSS are reported to the HFEA.’

We also know that an older study (there are no recent ones) at the Newcastle Fertility Centre, reported in Human Fertility, found that more than 20 eggs were collected from at least one in seven patients. 14.5 per cent of these women were admitted to hospital and nearly all reported symptoms consistent with OHSS. In other words, between 1999 and 2003 a total of 49 women were admitted to hospital. Life-threatening complications occurred in two women.

Moreover, there is still little to no peer-reviewed medical research on the safety effects of egg procurement on the health of the women. So this makes it impossible for clinics to provide adequate (let alone accurate) information for women to make informed choices relative to the health risks involved.

The lack of research and data is actually pretty shocking.  Egg donors need to know that long-term research simply is not there.

Even the tiniest risk of complication needs to be taken seriously, especially when dealing with 57 perfectly healthy young fertile women, who have no clinical need to undergo a potentially life-threatening procedure. Procedures with risk are performed on sick patients with the understanding that the benefits of the procedure outweigh the risks or the consequences of doing nothing.

But in egg donation for ‘three-parent’ baby research there is no medical benefit to the women, only risk.  Their only ‘benefit’ is therefore the £500 that the Newcastle researchers are paying them.

So who will put their health at risk for £500? Wealthy women rarely donate their eggs. Instead it is women who are disadvantaged, economically needy and/or infertile and vulnerable.

So why are so few feminists exposing how egg ‘donation’ exploits and harms women?

And why is the risk to the health of 64 young women (a number that will increase) missing from this debate?

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Philippa Taylor
Philippa Taylor
Philippa Taylor is Head of Public Policy at the Christian Medical Fellowship @PhilippaTaylor_

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